Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0309796
PubChem CID
Molecular Formula
C10H13NO2
Molecular Weight
179.219 g/mol
Synonyms/Alias
[37491-98-8; 2-Methyl-6;7-dihydroxy-1;2;3;4-tetrahydroisoquinoline; 2-methyl-1;2;3;4-tetrahydroisoquinoline-6;7-diol; 2(N)-Methyl-norsalsolinol; 1;2;3;4-Tetrahydro-2-methyl-6;7-isoquinolinediol; 2-met...
InChI Key
WETXYFNVBDLWIW-UHFFFAOYSA-N
InChI
InChI=1S/C10H13NO2/c1-11-3-2-7-4-9(12)10(13)5-8(7)6-11/h4-5,12-13H,2-3,6H2,1H3
IUPAC Name
2-methyl-3,4-dihydro-1H-isoquinoline-6,7-diol
CAS Number
54383-36-7

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

26 27 0 0 0 0 0 0 0 0999 V2000
-2.8419 0.3230 -0.6310 C 0 0 0 0 0 0 0 0 0 0 0 0
-2.2248 0.7285 0.6440 N 0 0 0 0 0 0 0 0 0 0 0 0
-1.9341 -0.419...

Experimental Data

Activity Data

Target Ion Channel
Neuronal acetylcholine receptor subunit alpha-3/beta-4
Uniprot Accession Number
Function
Antagonist
Species
Mus musculus (Mouse)
IC50
IC50: >1000000 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.4
Holding Potential
Not specified
Temperature
37 °C
Test Method
Fluorometric Imaging Plate Reader (FLIPR) Membrane Potential Assay
Test Species
tsA-201 Homo sapiens embryonic kidney cell

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
13
Rotatable Bonds
0
logP
1.0857
Complexity
49.8096
TPSA (Ų)
43.7
H-Bond Donors
2
H-Bond Acceptors
3
Ring Count
2
New Search